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Dr Ng Huck Hui
Department of Biological
Sciences, NUS & Genome Institute of Singapore,
A*STAR |
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"“For his research on gene regulation”"
Dr Ng studies the regulation of gene expression at
different levels: epigenetic, chromatin-mediated, and
transcription factor-driven. The control of gene expression is
important for every aspect of life. Inappropriate expression
can lead to various forms of diseases, including cancer and
developmental abnormalities. He had previously uncovered novel
links between transcription, chromatin and epigenetic
modifications. These works are of fundamental significance,
and have been highly cited.
Using cutting edge
technologies like RNA interference and chromatin
immunoprecipitation, Dr Ng’s research focus on identifying
novel targets of important transcriptional regulators. Coupled
with high throughput methodologies, the dense genomic level
data obtained will enable biologists to reconstruct the
regulatory networks in the cells and provide a global view of
molecular events happening in the cells.
Currently, Dr
Ng’s research focuses on two biological domains: stem cell and
cancer cell biology. The specification of different cell fates
requires a precise mechanism to control gene expression. Thus,
investigation along these lines may enable scientists to
derive cell types of interest.
For his research on
gene regulation, Dr Ng Huck Hui is awarded the Young Scientist
Award 2004.
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Nominations for 2004 has closed. The
next call will be in February 2005.
Find
out more | |
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Events 
