Lam Siew Hong (Lecturer) Contact Information: Department of Biological Sciences National University of Singapore 14 Science Drive 4 Singapore 117543 Email: dbslsh@nus.edu.sg

PhD NUS

Research interests:

Environmental Health Genomics, Disease Modeling, Toxicogenomics, and Systems Biology.

Selected recent publications

1. Lam SH, Winata CL, Tong Y, Korzh L, Korzh V, Spitsbergen J, Sinnakarupan M, Miller LD, Liu ET, Gong Z (2006). Trancriptome Kinetics of Arsenic-induced Adaptive Response in Zebrafish Liver. Physiological Genomics27(3):351-61 .

2. Lam SH, Gong Z (2006). Modeling liver cancer using zebrafish: a comparative oncogenomics approach. Cell Cycle. 5(6):573-7.

3. Lam SH, Wu YL, Vega VB, Miller LD, Spitsbergen J, Tong Y, Zhan H, Govindarajan KR, Lee S, Mathavan S, Murthy KR, Buhler DR, Liu ET, Gong Z (2006). Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. Nat Biotechnol. 24(1):73-5.

4. Zeng Z, Shan T, Tong Y, Lam SH, Gong Z (2005). Development of estrogen-responsive transgenic medaka for environmental monitoring of endocrine disrupters. Environmental Science and Technology 39(22):9001-8.

5. Mathavan S, Lee SG, Mak A, Miller LD, Murthy KR, Govindarajan KR, Tong Y, Wu YL, Lam SH, Yang H, Ruan Y, Korzh V, Gong Z, Liu ET, Lufkin T (2005). Transcriptome analysis of zebrafish embryogenesis using microarrays. PLoS Genetics 1(2):260-76.

6. Lam SH, Sin YM, Gong Z, Lam TJ (2005). Effects of Thyroid Hormone on the Development of Immune System in Zebrafish. General and Comparative Endocrinology 142(3):325-35.

7. Tong Y, Shan T, Poh YK, Yan T, Wang H, Lam SH, Gong Z (2004). Molecular cloning of zebrafish and medaka vitellogenin genes and comparison of their expression in response to 17beta-estradiol. Gene 328:25-36.

8. Lam SH, Chua HL, Gong Z, Lam TJ, Sin YM (2004). Development and Maturation of the Immune System in Zebrafish, Danio rerio: A Gene Expression Profiling, In Situ Hybridization and Immunological Study. Developmental and Comparative Immunology 28:9-28.

9. Lam SH, Chua HL, Gong Z, Wen Z, Lam TJ, Sin YM. (2002). Morphologic Transformation of the Thymus in Developing Zebrafish. Developmental Dynamics 225:87-94.