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Curriculum vitae
Curvularia
spores: common in outdoor air. Capable
of triggering allergenic responses
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TAN Teck Koon
(Associate
Professor)
Contact
Information:
Department of Biological Sciences
National University of Singapore
14 Science Drive 4
Singapore 117543
Tel: 65162855/4537
Fax: 67792486
email:
dbstantk@nus.edu.sg
Dean of Students, Office of Student Affairs, NUS |
PhD (Botany), 1980, University of Singapore
Research Interests:
Fungi impact on human life in many areas such
as health and wellness, agriculture, horticul-ture, biotechnology,
and food production. Knowledge in fungal biodiversity, fungal biology
and fungal ecology constitutes the fundamentals towards understanding,
exploiting and managing fungi in these different areas. The Mycology
and Fungal-Plant Interactions Laboratory focuses on the twin approach
of studying the biodiversity of local/tropical fungi, and the exploitation
of se-lected fungi. Under biodiversity studies, the present key
interests are in the aquatic and marine fungi of which about 200
local species have been recorded, and endophytic symbiotic fungi
of agricultural/horticultural relevance. Applied mycological interests
focus on fungal enzymes, fun-gal symbiosis in orchids, fungal chitosan,
and fungal airspora in relation to allergenic responses.
Current Projects:
Biodiversity and ecology of aquatic/marine fungi.
This is an on-going pursuit to document the local
tropical mycoflora, and to isolate strains of fungi for preservation
in the Fungal Culture Collection, from which specimens are drawn
for teaching and research. The coastal marine and mangrove fungi
around Singapore have been documented. Currently, the fungi associated
with marine soft corals are being studied and asso-ciated with this
is the investigation on anti-fungal extracts of these corals.
Fungal-Plant Interactions
The main interest is on the Rhizoctonia - Orchid
symbiosis. Aspects studied include the opti-mization for growth
and development of orchid seedlings and tissue cultures through
fungal sym-biosis, production of 'mycorrhizal-seeds', and the characterization
of symbiotic and pathogenic Rhizoctonia strains. We have shown that
mycorrhizal orchid seeds give a higher percentage germination and
better growth and development of seedlings, as compared to aseptic
germina-tion on synthetic media. Another interaction being studied
is that of the Pisolithus-Acacia mangium symbiosis.
Fungal allergens
The fungal airspora profile in various local neighbourhoods
has been mapped and based on this, highly allergenic spores of local
fungal species have been identified. These are different from typical
allergenic species reported in literature. Current work focuses
on spore imaging and the characterization of allergenic spore proteins.
Fungal chitosan
Chitosan is a polymer of pharmaceutical, medical
and industrial relevance. Chitosan produc-tion from fungi has certain
advantages over the only current mode of commercial production i.e.
from crustacean shells. Our current work is on the elucidation of
the chitin deacetylase gene involved in the production of chitosan
in Gongronella butleri. This is a continuation of work done to screen
fungi with good chitosan yields, optimization of chitosan production
in batch cultures, characterization of fungal chitosan, and mutation
to obtain high yielding fungal strains.
Selected Publications:
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Wang, Y, T K Tan, G K Tan, J D Connolly & L J Harrison. Microbial transformation of the sesquiterpenoid (-)-maalioxide by Mucor plumbeus. Phytochemistry, 67 (2006): 58- 61.
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Jayakumar, P & T K Tan. Phosphorus solubilization by ectomycorrhizal Pisolithus tinctorius in pure culture and in association with Acacia mangium. Symbiosis, 39 (2006): 125-139.
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Jayakumar, P & T K Tan. Changes during early ectomycorrhizal formation by Pisolithus tinctorius on Acacia mangium and their impact on nodule formation by Bradyrhizobium sp. Symbiosis, 40 (2005): 141-149.
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Jayakumar, P & T K Tan. Growth performance and nodulation response of Acacia mangium co-inoculated with Bradyrhizobium sp. and Pisolithus tinctorius. Symbiosis, 40 (2005): 109-114.
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Ma, M, T K Tan & S M Wong. Identification and molecular phylogeny of Epulorhiza isolates from tropical orchids. Mycological Research, 107 (2003): 1041-1049.
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Nwe, N, S Chandrakrachang, W Stevens, T Maw, T K Tan, E Khor & S M Wong. Production of fungal chitosan by solid state and submerged fermentation. Carbohydrate Polymers, 49 (2002): 235-237.
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Maw, T, T K Tan, E Khor & S M Wong. Selection of Gongronella butleri strains for enhanced chitosan yield with UV mutagenesis. Journal of Biotechnology, 95 (2002): 189-193.
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Maw, T, T K Tan, E Khor & S M Wong. Complete cDNA sequence of chitin deacetylase from Gongronella butleri and its phylogenetic analysis revealed clusters corresponding to taxonomic classification of fungi. Journal of Bioscience and Bioengineering, 93 (2002): 376-381.
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Tan T K. Shrinking mangroves, Thriving fungi. In: Fungi in Marine Environments, ed. K D Hyde, 235-246. Fungal Diversity Press, 2002.
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Chew, F T, S H Lim, H S Shang, M D Siti Dahlia, D Y T Goh, B W Lee, H T W Tan and T K Tan. Evaluation of the allergenicity of tropical pollen and airborne spores in Singapore. Allergy, 55 (2000): 340-347. .
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