Former Members

Postdoctoral Research Fellows

Daniel AIK (2023-2024): Transmembrane bilayer coupling in live cell — an Alex-Imaging FCCS study

ZHONG Jun (2023): Cross scale biophysics and mechanobiology

TANG Wai Hoh (2022-2023): Deep learning reduces data requirements and allows real-time measurements in Imaging FCS

Harikrushnan BALASUBRAMANIAN (2021-2022): Combinatorial DNA-PAINT for the Multiplexed Analysis of Cell Receptor Interactions

TAN Boon Wu, Aaron (2020-2022): Development of neuronal zebrafish primary cell culture and investigation of brain-cholesterol and sphingolipid bio-synthesis pathways

Sapthaswaran Veerapathiran (2019-2021): Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions.

Anjali GUPTA (2019-2020): To Hop or not to Hop: Exceptions in the FCS Diffusion Law.

Debjit ROY (2019): Investigation of the effects of ageing using Fluorescent Techniques.

Jagadish SANKARAN (2015-2019): Single microcolony diffusion analysis in Pseudomonas aeruginosa biofilms

NG Xue Wen (2017-2018): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and organization in vitro and in vivo by SPIM-FCS

Nirmalya BAG (2014-2016): Imaging fluorescence correlation spectroscopy studies lipid membrane dynamics and organization: applications to the investigation of lipid bilayers, cell membranes and membrane active peptides

Radek MACHÁŇ (2012-2016): Combining Super-Resolution and FRAP with Imaging FCS, Dual-color ITIR-FCCS

FOO Yong Hwee (2010-2011): Quantitation of biological interactions in living cells using single wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)

SHI Xianke (2008-2010): Applying fluorescence correlation spectroscopy in living zebrafish embryos

GUO Lin (2008-2009): Investigation of peptide-lipid interaction by fluorescence imaging and spectroscopy

Sebastian LEPTIHN (2007): Investigation of the Action Mechanism of Antimicrobial Peptides by Single Particle Tracking, Imaging, and Biochemical Methods

Lopamudra HOMCHAUDHURI (2006-2007): Lipid Membrane/Peptide Interactions

Balakrishnan KANNAN (2004-2007): EMCCD based FCS

Ph. D

Daniel AIK (2024): Real-Time Measurements of Biological Membrane Dynamics by Imaging Fluorescence Correlation and Cross-Correlation Spectroscopy

Bitan SAHA (2022): Investigating the morphogen dynamics and a novel role of BMP signalling during zebrafish development

YONG Xin Ee (2022): Molecular mechanism of dengue virus fusion and genome replication.

Harikrushnan BALASUBRAMANIAN (2021): Investigation of Epidermal Growth Factor Receptor (EGFR) organization and dynamics on plasma membrane of live cells using fluorescence techniques.

TANG Wai Hoh (2020): Using deep learning for fluorescence spectroscopy analysis, time series analysis and generation of synthetic tabular data.

Sapthaswaran VEERAPATHIRAN (2019): Mapping the Expression Dynamics and Interactions of WNT3 in Live Zebrafish Embryos Using Fluorescence Techniques.

Sarala Neomi TANTIRIMUDALIGE (2019): Investigation of Dengue Virus Dynamics and Cellular Attachment Using Fluorescence Cross-Correlation Spectroscopy and Single Particle Tracking.

Anjali GUPTA (2019): Role of membrane lipid composition in plasma membrane dynamics, organization and protein function

NG Xue Wen (2017): Quantitative three-dimensional (3D) mapping of biomolecular dynamics and organization in vitro and in vivo by SPIM-FCS

Andreas KARAMPATZAKIS (2017): Novel spectroscopic techniques for functional imaging of bacterial biofilms at microscopic level

Angela KOH (2017): Characterization of survival motor neuron dynamics by fluorescence correlation spectroscopy and neurexin2a function in a zebrafish model for spinal muscular atrophy

HUANG Shuangru (2016): Dynamics and organization of the epidermal growth factor receptor investigated by imaging fluorescence correlation spectroscopy

Sibel YAVAS (2016): Investigation of epidermal growth factor receptor in live cells by various fluorescence cross-correlation spectroscopy modalities

SUN Guangyu (2015): Application of bayesian model selection in fluorescence correlation spectroscopy (FCS) to Wnt3EGFP secretion and diffusion in zebrafish embryos

WANG Xi (2015): The study of nodal protein dynamics and interactions in living zebrafish embryos by fluorescence correlation and cross-correlation spectroscopy

Anand Pratap SINGH (2014): Light Sheet based fluorescence correlation and cross-correlation spectroscopy for quantitative measurements of bio-molecules in live cells

Nirmalya BAG (2014): Imaging fluorescence correlation spectroscopy studies lipid membrane dynamics and organization: applications to the investigation of lipid bilayers, cell membranes and membrane active peptides

MA Xiaoxiao (2014): Quantification of epidermal growth factor receptor dynamics and interactions in living cells by fluorescence correlation and cross-correlation spectroscopy

Rafi RASHID (2012):The biophysical properties of macromolecular crowders and their uptake, distribution and fate in cells

Tapan Kumar MISTRI (2012): Quantitative determination of the assembly of the Oct4-Sox2-DNA ternary complex and its relevance to pre-implantation development

Jagadish SANKARAN (2012): Imaging Fluorescence Correlation Spectroscopy: theory, simulations and applications to probe lipid-membrane dynamics

FOO Yong Hwee (2011): Quantitation of biological interactions in living cells using single wavelength fluorescence cross-correlation spectroscopy (SW-FCCS)

Manoj Kumar MANNA (2011): Identification of lipid nano-domains using FCS and ITIR-FCS on live cells

SHI Xianke (2010): Applying fluorescence correlation spectroscopy in living zebrafish embryos

GUO Lin (2010): Investigation of peptide-lipid interaction by fluorescence imaging and spectroscopy

PAN Xiaotao (2009): Investigation of microfluidics in channels and tissues by fluorescence correlation

LIU Ping (2008): The study of interactions of transmembrane receptors and intracellular signaling proteins in live cells by fluorescence correlation and cross-correlation spectroscopy

YU Lanlan (2007): Investigation of the interaction of antimicrobial peptides with lipids and lipid membranes

HWANG Ling Chin (2007): Single wavelength excitation fluorescence cross-correlation spectroscopy

M. Sc/Diploma

Divya DHASMANA (2023): Understanding the protein dynamics of Frizzled and Wnt in embroyonic development

CHONG Hao Han (2023): Design of novel GTP sensor based on the ε-subunit from Bascillus species

ZHAO Wan Yu (2022): Towards the design of GTP metabolic sensor based on the ATP synthase epsilon chain ε-subunit from Bacillus species

SIM Shao Ren (2022): Imaging FCS analysis using Convolutional Neural Networks

Kavitha RAJASEKHAR (2022): Investigation of dynamics of midkine and pleiotrophin during zebrafish development using FCS

LIM Shi Ying (2015): Investigation of cell membrane dynamics and organization by Imaging FCS

FAN Kaijie Herbert (2014): Measuring diffusion and quenching in microchannels

TEO Lin Shin (2012): Investigation of membrane properties in the central nervous system of Drosophila melanogaster studied by fluorescence correlation spectroscopy

TAY Wee Beng (2011): Production of laboratory video protocols for teaching purposes

Diane S. MORGAN¹ (2006): Three dimensional flow profile measurements in microstructures using fluorescence correlation spectroscopy

LI Xinheng (2005): Synthesis and characterization of biofunctionalized gold nanoparticles

Anne THIEBAUD¹ (2004): Dual-colour single molecule detection

NIU Lifang (2005): Strategies for detecting and studying biomolecules using surface plasmon fluorescence microscopy and spectroscopy
¹Exchange student from Swiss Federal Institute of Technology Lausanne (EPFL); co-supervision with Prof. Theo Lasser.

Research Assistants

Indira KARTIGAYEN (2018-2021): Enabling live imaging based developmental studies in zebrafish through transgenesis in terms of molecular based techniques

Catherine TEO Shi Hua (2013-2015): Study of cytoskeletal dynamics using multi-functional super-resolution imaging

LIU Jun (2005-2010): Study of lipid-peptide interaction using fluorescence spectroscopy

B. Sc(Hons. )

Muhammad Syakir Bin Mohamed Tajudin (2023): Wnt and Wntless interactions throgh Fluorescence (Cross) Correlation Spectroscopy

Nafeesah Binte Mohamed Ibrahim (2021): Oligomerization and Dynamics of Frizzled receptors investigated by fluorescence methods

Daniel AIK (2019): Application of Fluorescence Correlation Spectroscopy to understand the impact of additives on the micellar assembly of bar and liquid hand soaps

CHOW Su Tzen (2019): Cell Viability after Transfection Tested by Membrane Dynamics and Organization

GOH Jie Hui Corinna (2018): Epidermal Growth Factor Receptor Membrane Dynamics and Organization in Plasma Membranes Investigated by Fluorescence Spectroscopy

FAN Ricci (2018): Physico-chemical properties of emulsions studied by fluorescence spectroscopy

BUT Ka Pui (2018): Probing antibiotic diffusion in bacterial biofilms using a biofilm mimic

KOH Kai Jie (2017) : The investigation of peptide membrane interactions by imaging Fluorescence Correlation Spectroscopy

KWONG Mei Lin (2017) : Investigation of the action mechanism of the antimicrobial peptide, Aurein 1.2, by fluorescence spectroscopy

KOO Haoming (2017) : Experimental demonstration of a bio-laser

OWH Wei Le (2017): Anisotropy imaging to probe cell membrane dynamics and organisation

ONG Wei Yee (2016): Investigation of dengue proteins using fluorescence spectroscopy

LIU Yanting (2016): Determination of dimerization of Epidermal Growth Factor Receptor using genetic tags in live cells

TAN Jianwei Benedict (2015): Structural dynamic of dengue virus by single-molecule FRET

SIM Chun Siang (2015): Investigation of cell membrane organisational asymmetry by imaging fluorescence correlation spectroscopy

LAU Jing Yi Clara (2015): Investigation of lipid droplet fusion in live cells

Syed Hassan B SYED ZAINAL (2015): The measurement of molecular interactions using fluorescence cross-correlation spectroscopy

LIM Shi Ying (2014): Investigation of cell membrane structure and organization by fluorescence correlation spectroscopy

TOH Kah Huay Caroline (2013): Measuring reactions in microchannels

YAP Hui Xin Darilyn (2013):The measurements of lipid bilayer and cell membrane dynamic between 20-40^oC by fluorescence spectroscopy

NG Xue Wen (2013): Dynamics and interactions of the transcription factors c-Fos and c-Jun in cell nuclei determined by fluorescence cross-correlation spectroscopy

FAN Kaijie Herbert (2012): Measuring diffusion and reactions in microchannels

Md Na'Im B SA'DOLLAH (2010): Single molecule fluorescence studies for the determination of protein dynamics on cell membranes

GOH Jun Lee (2010): Investigation of Cell Motility and Membrane Diffusion by Imaging Fluorescence Correlation Spectroscopy

NG Wei Ping (2010): Quantification of dimer formation between transcription factors on specific DNA elements

LOW Wei Wen (2010): Effect of Crowders on the Diffusion And Polymerisation of Actin.

ONG Li Bing (2008): Determination of the Action of Antimicrobial Peptides

SIOW Li Yan (2008): Rotational fluorescence correlation spectroscopy for the study of biomolecules

GOH Beng Hwa (2008): Measuring Reactions in Microchannels

SOH Xinyi (2008): Investigation of Cell Membrane Heterogeneity

ANG Kailian, Priscilla (2008 co-supervision): Assessing the Biocompatibility and Biosensing Property of Supported Lipid Bilayer on Diamond

LOW Qin Tian (2007): Measuring Reactions in Microchannels

CHOH Thian Fong, Carissa (2007): Cell membrane heterogeneity as seen by different molecules

YANG Shihong (, co-supervision): Quantifying microchannel cell transport with confocal fluorescence correlation spectroscopy

HONG Yi Mian (2006) : Molecular Diffusion Measurement In Lipid Bilayers Over Wide Concentration Ranges – A Comparative Study

LIM Wanrong (2006) : Determination Of Biomolecular Interactions By Fluorescence Cross-Correlation Spectroscopy

FOO Willy (2005) : Investigation Of Epidermal Growth Factor Receptors In Living Cells By Fluorescence Spectroscopy

AW Cai Li, Jade (2005): Characterization Of Graft-Polymerized Surfaces By Fluorescence Correlation Spectroscopy

FOK Han Yew, Marcus (2005): Rotational Fluorescence Correlation Spectroscopy For The Study Of Biomolecules

TAN Minyi,Shawn (2004): Determination Of The Aggregation Number Of Lipopolysaccharides By Fluorescence Correlation Spectroscopy

FOO Yong Hwee (2003): Interaction Of Antimicrobial Peptides With Lipid Membranes: A Model Membrane Study

Visitors

Ping QIN (Hong Kong Baptist University, Hong Kong, 2023 - 2024, 2 months)

Lisa POLZER (Freie Universität Berlin, Germany, 2023, 4 months)

LEE Donghwa (National University of Singapore, Singapore, 2023, 4 months of Undergraduate Research Opportunities Programme in Science)

Nandula Gopal Krishna (Science Research Program (highschool), Singapore, 2023, 2 months)

Lukas TAN Zheng Jie (Science Research Program (highschool), Singapore, 2023, 2 months)

Ian WANG (Science Research Program (highschool), Singapore, 2023, 2 months)

WEI Minping (China, 2021 - 2022, 1 year)

Zahra (Nadia) SAADATMAND (La Trobe University, Australia, 2019 - 2022, 3 years)

Sarah Man Sze CHENG (The Hong Kong University of Science and Technology, Hong Kong, 2022, 2 months)

Diptatanu DAS (Indian Institute of Science Education and Research, Kolkata, 2021 - 2022, 5 months)

Akshat LOHIYA (Indian Institute of Technology, Delhi, 2021, 3 months)

Danqin LU (East China Normal University, China, 2019 - 2020, 1 year)

Yuting LI (University of Science and Technology of China, China, 2019, 2 months)

Ryosuke FUKUSHIMA (Hokkaido University, Japan, 2019, 2 months)

Dominic SCHATZ (Germany, 2 months)

Sonia MONTI (ZHdK Zürich, Switzerland, 2018, 6 months)

Sonja PAPAN (Marie-Curie-Gymnasium Dresden, Germany, 2018, 1 month)

Stefanie HACKL (Universitaet Wien, Austria, 2018 and 2016, 2 months each)

Madlen LUCKNER (Humboldt-Universität zu Berlin, Germany, 2018, 1 month)

Fariha RAHMAN (University of Toronto, 2017, 12 weeks)

Marie-Lena HARWARDT (Goethe-University Frankfurt, Germany, 2017, 15 weeks)

Ann-Christin ANDRES (Universitaet des Saarlandes, Germany, 2017, 2 months)

Andreas GRUETER (Universitaet des Saarlandes, Germany, 2016, 3 months)

Peter TÖRÖK (Imperial College, London, 2016, 3 weeks)

Amy WON (University of Toronto, 2016, 1 week)

Peter TÖRÖK (Imperial College, London, 2015, 2 weeks)

DONG Chaoqing (Shanghai Jiao Taong University, China, 2015, 1 week)

Abhay SHARMA (Indian Institute of Technology, Guwahati, India, 2015, 2 months)

Lavanya PAWAR (Indian Institute of Technology, Guwahati, India, 2015, 2 months)

Patrick KRAMER (University of Notre Dame, USA, 2013 - 2014, 10 months, funded by US Fulbright Scholarship)

Tejaswi TAMMAREDDY (Andhra University, India, 2014, 8 weeks)

László VÍGH (Hungarian Academy of Sciences, 2013, 1 week)

Zsolt TÖRÖK (Hungarian Academy of Sciences, 2013, 1 week)

Imre GOMBOS (Hungarian Academy of Sciences, 2013, 1 week)

Antonija BURČUL (Zagreb University, Croatia, 2012, 4 months)

Bill Söderström ARNFLO (Stockholm University, Sweden, 2 weeks)

Aseem MISHRA (International Centre for Genetic Engineering and Biotechnology, India, 2012, 6 months, funded by Wellcome Trust-DBT India Alliance Early Career Fellowship)

Klaus YSERENTANT (University of Heidelberg, Germany, 2012, 4 months)

Adam OPALSKI (Warsaw University of Technology, Poland, 2012, 3 months)

Alok BHARTI (International School of Photonics, India, 2012, 3 months)

Alexandra PAUL (Universitaet des Saarlandes, Germany, 2011, 3 months)

K.V.S NARAIN (Indian Institute of Technology Roorkee, India, 2011, 8 weeks)

ZHANG Yiwen (Nanjing University, China, 2011, 10 weeks for final year project)

Jan KRIEGER (German Cancer Research Center, DKFZ, Germany, 2010, 2 weeks)

Thomas ELLINGHAUS (Universitaet Tübingen, Germany, 2009, 8 weeks)

Dagmar AUERBACH (Universitaet des Saarlandes, Germany, 2008/9, 3 months)

Shane Mason HODGE (University of Toronto, Canada, 2008, 5 weeks)

Marian ADAMSON (University of Michigan Ann Arbor, USA, 2007, 3 weeks)

Ming Yong (University of Michigan, Ann Arbor, USA, 2007, 3 weeks)

Corneliu BALAN (Polytehnica Bucharest, Romania, 2007, 2 weeks, funded by EERSS)

Mihaela GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2005, 1 month, funded by EERSS)

Eugen GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2005, 1 month, funded by EERSS)

Eugen GHEORGHIU (International Centre of Biodynamics, Bucharest, Romania, 2004, 2 weeks, funded by EERSS)