CBIS CryoEM: JEOL 2200FS
The new TEM is equipped with field emission gun, high resolution cryo-pole-piece, in-column omega energy filter and Zernike phase plate, and latest electron DE-12 direct detector. By using Zernike phase plate, the sin-shape of contrast transfer function will be converted into cosine-shape instead and the low-resolution information is high naturally. Hence, the visibility of biological specimens will be enhanced dramatically. Particularly, specimens less than 200kDa which are hardly visible with normal cryoEM will stand out very well with the phase plate. The microscope will be used for research projects that study protein complexes, virus, virus-like particles, bacterial, and cell and tissue specimens at both liquid nitrogen temperature and room temperature.