BL5232 Introduction to Bioimaging
Professor Thorsten Wohland
4 units, Semester 2
Bioimaging is one of the major emerging research areas in biological research due to the wide range of methods available with excellent temporal and spatial resolution. This allows us nowadays to test biological events at the single molecule level. The module aims at introducing the interested student to basics in the field. It will cover the basic physical principles of light microscopy, will have some hands-on components for the students to test their theoretical knowledge in practice, and will introduce basic image treatment concepts through practical training on widely used image treatment programmes.
BL5232A Practical Bioimaging A: Light & Electron Microscopy
Associate Professor Cynthia He, Assistant Professor Luo Min
4 units, Special Term
Bioimaging is one of the major emerging areas in biological research due to the wide range of methods available with excellent temporal and spatial resolution. This allows us to test biological events at both the single-cell and single-molecule level. The module aims at introducing the interested student to the practical basis to achieve good images in both light microscopy and electron microscopy. Students will perform hands-on experiments in the Centre of Bioimaging Sciences and will get a basic training in sample preparation and image data analysis.
BL5232C Practical Bioimaging C: Hands-on Microscopy
Professor Thorsten Wohland, Assistant Professor Duane Loh
2 units, Special Term
Bioimaging is one of the major emerging research areas in biological research due to the wide range of methods available with excellent temporal and spatial resolution. This allows us nowadays to test biological events at the single molecule level. The module aims at introducing the interested student to the practical basis to achieve good images in microscopy. Students will construct their own microscopes and perform hands-on experiments on the different microscopes in the Centre of Bioimaging Sciences and will get a basic training to allow them to take images independently.
BL5611 Advanced and Current Topics in Drug Development
Assistant Professor Tan Yong Zi
4 units, Semester 2
Covers advanced and current topics in drug development, in particular on engineered cell therapies, GPCR and structure-based drug design, AI, peptides and RNA therapeutics.
CM4236 Spectroscopy and Imaging in Biophysical Chemistry
Assistant Professor Zhao Ziqing, Winston
4 units, Semester 2
Biology has become a quantitative science that requires a broad understanding of the physico-chemical methodologies and principles that underpin life processes. This module introduces the fundamental concepts and techniques from physical chemistry that are most relevant to biology, and apply them to a variety of biomolecular and cellular systems. In addition to important tools from optical spectroscopy/imaging (including fluorescence, FCS, FRET, FRAP, single-molecule and super-resolution microscopy), it will also cover key principles in biomolecular binding and cooperativity, molecular diffusion, biochemical kinetics, and statistical and stochastic approaches in biophysical chemistry. These concepts and techniques will be illustrated with a wide selection of applications, ranging from enzyme catalysis to molecular motors and to gene expression.
LSM3234 Biological Imaging of Growth and Form
Associate Professor Cynthia He, Assistant Professor Luo Min
4 units, Semester 1
Growth and form are fundamental to all living organisms, crucial to health and diseases. Development in imaging methods and tools has transformed biological and biomedical sciences. This course will introduce basic concepts in imaging and their applications. The major topics include basic optics, light and electron microscopy, fluorescence and related methods. Introduction of each imaging technology will be linked with a set of biological problems of fundamental interests and biomedical implications.
LSM4231 Structural Biology
Professor Yang Daiwen, Professor Jayaraman Sivaraman, Assistant Professor Tan Yong Zi
4 units, Semester 2
Covers X-ray crystallography, NMR and cryo-EM as structural biology techniques.